Welcome to Best Western Mystic Hotel The Best Western Mystic Hotel is located in the heart of historic Mystic, Connecticut, and the state's number one tourist destination. Settled as a shipbuilding center in the 1650's, Mystic is known around the globe for its maritime heritage and its ties to the sea. Whether you are traveling to the area to visit the world's largest gaming casino or to enjoy the region's many historical attractions, Mystic is the perfect choice for a well rounded vacation or a business and convention getaway. The best place to stay is the most conveniently located hotel in Southeastern Connecticut The Best Western Mystic Hotel is located within five blocks of the Mystic Seaport Museum, the Mystic Marine life Aquarium and the Olde Mystick Village. Foxwoods Resort Casino and the Mohegan Sun Resort Casino are only minutes away. Take a ride aboard a windjammer cruise or tour America's first nuclear powered submarine. Every season offers something different and all major attractions are open year-round.