Easy on & off interstate access. The Comfort Inn & Suites is conveniently located less than one mile from the Orangeburg Regional Medical Center. This Orangeburg hotel is close to popular area attractions, including South Carolina State University, Santee State Park, Edisto Memorial Gardens, Claftin College and Lake Marion. Full-service amenities include free continental breakfast, free local calls, free USA Today, outdoor pool and high-speed Internet access. Free guest passes to a nearby fitness club are available. Pet accommodation: 20.00 USD per night. Pet Limit: 2 Pets per Room.